Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging and an additional 2 car off street parking in front of the house. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.
Single-familyProperty Type
1895Year Built
3,500 sq ftLot Size
$613Price/Sq.Ft.
2 car garageParking
Listed by Jill Penna•DRE #01895080• Christie's International Real Estate Sereno
Super walkable location with a detached two car garage behind the property. Elegant renovation with high ceilings, expansive modern kitchen, and multiple bedroom suites. Basement provides a lot of additional storage.
Downtown South San Francisco, located between Grand Avenue and Oyster Point Boulevard, is a historic and walkable South San Francisco neighborhood with a classic main-street grid and hillside bay views. The neighborhood’s character concentrates around Grand Avenue at Linden Avenue, where taquerias, old-school bakeries, espresso counters, and small storefronts keep the sidewalks active. Community pillars include the South San Francisco Conference Center, Orange Memorial Park, and the South San Francisco Public Library’s Main Library. Early-20th-century cottages and mid-century apartments mix with newer infill along the commercial spine. Caltrain at South San Francisco Station and the nearby BART connection shape a commuter-friendly rhythm. Parks and civic buildings give the district a grounded, everyday feel.
Provided by Walk Score and Local Logic
Offer insights
643 Grand Ave · $998,888
$1.02M and above
75% chance or better to win
Why $1.02M+ is a strong offer
DAYS ON MARKET
50 days
The average home goes pending in 13 days.
SALE-TO-LIST
105.5%
Most homes are selling 6% above list price.
About offer insights
Property details
Interior
Exterior
Finance
Kitchen
Bathroom
Bedroom
Living
Dining
Interior features
Skylights
Walk-in closet
Bedrooms
Primary bedroom on ground floor
Bathrooms
Four full bathrooms
Full bathroom on ground floor
Kitchen
Dishwasher
Garbage disposal
Refrigerator
Water softener
Laundry & utility
Washer and dryer included
Flooring
Hardwood
Heating & cooling
Central forced air heating
Exterior features
Electric vehicle Level 2 (240V) hookup
Walkable neighborhood (Walk Score: 82)
Home design
Two-story home
Parking
Detached garage
Two garage spaces
Off-street parking
On-street parking
Construction
Shingle roof
Slab foundation
Built in 2 (year value provided as '2' — original year not specified)
Utilities
Public water
Public sewer
Public gas/utilities
Electricity and solar
View estimated energy costs and solar savings for this home
Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging and an additional 2 car off street parking in front of the house. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.
Public Records
Dec 1, 2022
Sold
$1,309,000
$803/sq ft
MLSListings #ML81415816
Sep 2, 2014
Sold
$560,000
$344/sq ft
Jul 18, 2014
Pending
—
Jun 25, 2014
Price Changed
$549,000
$337/sq ft
Jun 25, 2014
Relisted
—
Jun 25, 2014
Pending
—
Jun 25, 2014
Price Changed
$549,900
$337/sq ft
Jun 7, 2014
Price Changed
$599,000
$367/sq ft
May 8, 2014
Listed
$625,000
$383/sq ft
May 8, 2014
Listed
$549,900
$337/sq ft
+12
Don't let exterior fool you this is a spacious 1895 2 story Victorian with all the Original Charm Intact. Home has 3 bedroom 2 bath with lots of light and High Ceilings. New Washer/ Dryer in Laundry off kitchen. Bedroom down has generous Walk In Closet.Oversized 2 Car with Alley Access. Glass and Iron door in Foyer is from The San Francisco Spreckles Mansion. First Time on market since 1945
Year
Property tax
Land + Additions
Assessment*
2025
$15,489 (+0.7%)
$848,966 + $540,034
$1,389,000
2024
$15,385 (+1.4%)
$832,320 + $529,446
$1,361,766
2023
$15,167 (+104.9%)
$816,000 + $519,065
$1,335,065
2022
$7,401 (+1.3%)
$800,000 + $508,888
$1,308,888
2021
$7,304 (+1.3%)
$317,106 + $317,106
$634,212
2020
$7,212 (+1.1%)
$310,889 + $310,889
$621,778
2019
$7,135 (+2.4%)
$307,702 + $307,702
$615,404
2018
$6,965 (+2.7%)
$301,669 + $301,669
$603,338
2017
$6,783 (+2.2%)
$289,955 + $289,955
$579,910
2016
$6,637 (+1.7%)
$289,955 + $289,955
$579,910
2015
$6,528 (+482.9%)
$284,270 + $284,270
$568,540
2014
$1,120 (+0.9%)
$17,987 + $38,980
$56,967
2012
$1,110 (+1.5%)
$17,906 + $38,804
$56,710
2011
$1,093 (+2.9%)
$17,555 + $38,044
$55,599
2010
$1,062 (+8.1%)
$17,211 + $37,299
$54,510
2009
$983 (+10.1%)
$17,083 + $37,021
$54,104
2008
$892
$17,124 + $37,109
$54,233
Public record
Public record
Zoning
Permits
Beds
3
Baths
1.5
Stories
2
Lot width
—
Lot depth
—
Lot size
3,500 Sq. Ft.
Year renovated
—
Finished Sq. Ft.
1,630
Unfinished Sq. Ft.
—
Total Sq. Ft.
1,630
Year built
1895
Style
Single Family Residential
County
San Mateo County
APN
012241120
Parking Spaces
—
Basement
—
Accessible
—
HOA Dues
—
Garage
—
Features
—
Last updated by owner on Sep 2, 2026.
DRM
Downtown Residential Medium District
The DRM District provides for attached or detached single-family housing, duplexes, triplexes, fourplexes, townhouses, care facilities, family day care, park and recreation facilities, and civic and institutional uses in the Downtown. The DRM District implements the General Plans Medium High Density Residential land use designation.
Permitted uses
Include but are not limited to:
Garden center
Day care facility
Housing-Multiple units
Housing-Senior
Housing-Other
Infrastructure
Recreation
Park & open space
Nov 28, 2023 • Final
Encroachment
Perform a full replacement of the sewer lateral.
Plumbing
Oct 25, 2023 • Final
Furnace
Replace a furnace in the same location.
HVAC
Permit history is from public records and may be incomplete or inaccurate. Redfin and its agents make no representations about the property condition or permit status. Buyers should independently verify all information.
Climate risks
1/10 Flood Factor
Minimal risk of a flood reaching the building in the next 30 years
1/10 Fire Factor
Unlikely to be in a wildfire in next 30 years
2/10 Heat Factor
8 days above 78° expected this year, 18 days in 30 years
1/10 Wind Factor
Minimal risk of severe winds over next 30 years
7/10 Air Factor
13 unhealthy days expected this year, 13 days in 30 years
Provided by First Street
Historical weather
South San Francisco, CA • 94080
Average low and high temperatures (°F)
61
48
62
49
66
51
63
51
65
52
66
54
67
56
67
57
70
60
70
56
63
51
59
49
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Sun exposure
61/ 100
Moderate sunlight
Sunscore
There appears to be some shading by surrounding buildings, terrain, and vegetation.
7 hrs
4.5 hrs
JuneDecember
Provided by Shadowmap
Redfin Estimate for 643 Grand Ave
$1,132,788
$134K over list price of $999K
Nearby comparable homes
The Redfin Estimate uses 6 recent nearby sales, priced between $1.2M to $1.3M.